Michelin has confirmed plans to close her Dundee tire factory by mid 2020, saying that the site is no longer financially viable.
The factory, which opened in 1971 and generates 16-inch tires and less for cars only, currently employs 845 people.
Michelin has been blaming the closure at a drop in demand for premium tires of 16 inches and less, as well as an increasing competition of low-cost alternatives manufactured in Asia.
Employees were told about the closure this morning meeting, following unrefined media reports on Monday.
SNP finance secretary, Derek Mackay, said: "Boring news not only for those working in the Michelin plant, but their families and the whole Dundee city."
"My main priority is on trying to find a sustainable future for the site, which will safeguard jobs and I will not leave any unimportant stone."
The decision to close the factory is a major recovery for Dundee, which has seen a clear revival following decades of difficulty due to the loss of industrial employment. In October, the new Dundee V & A museum, which cost £ 80m, welcomed its 100,000 visitors.
Unite Scotland's trade unions described the closure as a "hammer blast" for the city.
Michelin said: "The priority now is to provide the most effective support possible to 845 employees of the factory that can enable them to face the results of this difficult decision."
"In accordance with UK legislation, Michelin will start a consultation process with employees, employee and trade union representatives on the closure project, and on social support measures over the next two weeks," the company added.