Since the introduction of two polio vaccines 60 years ago, this terrible disease has gone out of killing millions (and falling much more) to be abolished close. Yet, the gap between almost going and complete the abolition of the virus is difficult to bridge. Provided that small reserves of such infectious diseases survive, there is an opportunity that he might rush back.
The removal barriers include anti-vaccination Western and Islamic fundamentalists oppose modern medicine, but there are also technical challenges. Vaccines need refrigeration, which are not easily accessible without electricity networks. Devoting a stable vaccine at room temperature can be a game changer.
"Stabilization is not a rocket science, so most academics do not pay much attention to this area," said Woo-Jin Shin from the University of South California as a statement. "However, no matter how great a drug or vaccine is, if it's not enough to transport it, it does not make anyone good."
The first author of the paper is Shin in Bio who publishes a stable polio vaccine, one that is effective after being stored for four weeks at room temperature. There is nothing new to the concept. Measles, frozen and meningococcal freezing have allowed them to be distributed to many remote locations, helping to turn the tide on these infections.
However, the previous attempts to frozen-dried and rehydrating polio vaccines did not harm their effectiveness and the methods used in other cases did not work. Shin found a way around that using laboratory techniques that allowed much faster tests of ingredients combinations.
With only 22 polio cases reported worldwide last year – and the current vaccines and mobile solar power units are hoping to end the work – the wide application of Shen's work is far from warranty
Even if this is true, however, the techniques used here may apply to freeze drying of vaccines or difficult medications. The work happened as Shin's supervisor, Professor Jae Jung, had spoken to a friend of student days, Dr Byeong S. Chang, who is now running Integrity Bio, a company that works on stabilization.
"He and I decided to do this because we are old and we need to contribute directly to health and human life," said Jung. "Creative ideas always start with food and drink."
Shin worked on the non-active virus, which is introduced through injection, which formed the original development against polio. The easier administered oral vaccine, which uses weakening form and virus, supersedes this mainly for a period. However, the weakening virus causes paralysis in three cases per million doses, leading some countries to change back to the original.