Saturday , July 2 2022

How does the immune response interact with "murderous diseases" at different times of the day?



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Experts say that our immune responses are controlled by the body's biological clock throughout the day, making the disease more serious for those who have infected at certain times of & t Night time.

How the immune response interacts TEXTILE – Young Reporters News Agency Agency – The biological clock controls the body's immune responses, 24 hours, and regulates sleep and surveillance regularly, the sleep cycle like it's called / wake up.

In Switzerland, researchers analyzed a range of studies, particularly those in mice, and found adaptive immune responses under biological control.

The researchers found four different cases which were more prevalent at certain times of the day: heart attack, pneumonia, parasitic infections and asthma attacks.

– Heart attack: in the morning

The findings, published in the magazine Trends in Immunology, show that a heart attack is more common in the morning and tends to be more serious than night.

The number of white blood cells resistant to bacteria, viruses and fungi is high during the day.

At night, they are high in the dead heart tissue, which means there is not a lot of cardiac protection at the time of comparison with the morning.

– Pneumonia: Afternoon

The researchers found that the bacterial poisoning associated with pneumonia started an inflammatory lung response of mice in the afternoon, and the researchers noted that immune cells could recruit more white blood cells in the peritoneal cavity, t the spleen and liver in the afternoon, That time.

– parasitic infections: with night

The results showed that parasitic infections were also time dependent. Studies in rats infected with intestinal parasites "Trichuris muris" in the morning were able to kill worms more quickly than infected mice with night.

The symptoms of allergies follow a daily rhythm, a condition that worsens generally between midnight and early morning. Experts say they have found airway inflammation in mice, which may be related to increased risk of overnight asthma attacks.

"It should apply to clinical applications," said principal author Christoph Sherman of the immunology department of Geneva University.

In humans and mice, researchers noted that white blood cells vary every day on a 24-hour basis. This raises the question of whether one day is possible to improve the immune response through consciousness. The methods of using the biological clock.

"Investigating biological rhythms in intrinsic and adaptive immunity is a great tool for understanding physiological interactions in general, and the sequence of events that depend on time when producing immune responses," Sherman said.

"The challenge is how to lead our growing understanding of daily immunology to bespoke treatments for human patients."

Source: The Sun
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