Tuesday , April 20 2021

Molnupiravir: A new drug could prevent corona transmission




Atlanta –

In addition to the large number of positive vaccine reports in the past few days, researchers in the USA are now heartened by other positive corona news: They claim to have developed a drug that prevents the virus from being spread. transfer. That would be a real breakthrough!

Scientists from Georgia State University in Atlanta, USA, are probably on a major case: According to the Italian news agency Ansa in the journal Nature Microbiology, they have developed an antiviral drug that could interfere with the transmission of coronavirus. The special feature: the active ingredient can be taken orally.

Corona: Molnupiravir could prevent virus transmission

The agent, which has only been tested on ferrets, prevents reproduction of the virus in the body within 24 hours. Therefore it cannot spread throughout the body.

According to the scientists, the data can also be transmitted to humans – the first studies with volunteers are already underway. This would mean that people infected with corona are no longer infectious after taking their drug called molnupiravir within a maximum of 24 hours.

According to the researchers, this could have a multiplier effect: it would prevent a serious course of the disease in infected people, significantly shorten the stage of infectivity, thereby rapidly bringing local epidemics under control and reducing emotional and economic consequences- quarantine social.

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The agent is “the first drug available orally that can block the rapid transmission of Sars-CoV-2,” said Richard Plemper, one of the scientists involved in the research. Molnupiravir could “change the game”.

This is how the researchers tested the drug

But how does that work out exactly? The researchers locked up several Covid-19-containing ferrets along with healthy products. Some of the sick animals received molnupiravir, and the other a placebo.

Subsequent tests showed that the ferrets treated with molnupiravir did not transmit the disease, but the untreated animals infected others with the virus.

Molnupiravir was already used on a trial basis during the corona pandemic

The drug, which is said to work similarly to Remdesivir, was originally developed to treat influenza infections. However, as early as April 2020, a study found that molnupiravir can prevent and reduce severe lung damage in corona-infected mice.

The product from manufacturer Ridgeback Biotherapeutics is currently in phase II / III clinical studies. It will probably take until the middle of next year until it has cleared all the necessary barriers for approval and can be used.




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