Monday , June 27 2022

Medicine helps young people control nuts


"There are exciting results that improve the image of incentive tolerance in some patients. I think well that the future treatment can be approved," says Göran Wennergren, a children's allergy at Drottning Silvia's Children and Youth Hospital, in Gothenburg, to the newspaper.

It has been known earlier that patients with peanut allergy can develop tolerance if they take up very small amounts of peeled and gradually increasing.

Researchers have now taken advantage of this and have developed biological oral immunotherapy where low doses of peanut protein are given in capsules or dosage bags.

Year of treatment

More than 550 patients of different ages, who took part in the current study, could either get nuts or placebo proteins in increasing doses. The aim was for the patient to achieve 600 milligrams of peanut protein, which corresponds to two or more nuts.

After about one year of treatment, the 67 per cent was tolerated in the drug group for patients aged between 4 and 17, while the corresponding figure was 4 per cent in the placebo group.

"It does not mean that the person does not have life-threatening reactions if something happens with the remains of nuts," said Göran Wennergren.

Surprisingly, there was no tolerance to see in the participants over the age of 17, something that Göran Wennergren believes with the immune system may be more influential in young people.

A British researcher states that the study, published in the New England Journal of Medicine, has set up well, but also suggests that he leaves some unanswered questions. For example, what happens when the treatment ends.

– Then tolerance is likely to drop. Patients need to have a small protein of nuts daily to maintain tolerance tolerance. This is a lifelong treatment, "said Göran Wennergren.

Fact: To hang out with dangerous nuts

In Sweden, the Swedish Food Safety Agency writes that small children with a risk of allergy to peanuts can be mixed, for example, yogurt or peanut butter in small pieces. Abroad, the advice is that these children should "have" nuts.

According to US guidelines, introduced by the National Institute of Allergy and Infectious Diseases, children with a high risk of peanut and / or allergy of eggs should taste 4 to 6 month old nuts. However, these children should meet with an expert before tasting.

For low or medium-sized children, nuts should be introduced from six months of age and children do not need to meet an expert.

Because children can put nuts in their throat, parents are advised not to put whole peanuts. Small spoonful pepper butter, peanut soup or nuts are fine in yoghurts.

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