Changes to the brain associated with Alzheimer's disease can occur up to 30 years before the first identifiable symptoms of the disease appear, completing a study published by the magazine. Boundaries in Neuroscience Aging.
Scientists at Johns Hopkins University say it is possible to use images of the brain and analyze serebrospol fluid to assess the risk of the disease at least 10 years before the most common symptoms, such as mild cognitive impairment, occur.
In order to develop the research, the medical records reviewed 290 people over 40 years of age drawn up by the National Health Institutions and the University of America School of Medicine.
Most adults at least one had a first degree relationship with dementia with Alzheimer's disease type, putting them at higher risk than usual, Laurent Younes, one of the authors of the research, explained.
The serebrospol liquid specialists also collected MRI brain scans from the study participants every two years between 1995 and 2005. They also performed five standard tests of memory, learning, reading and attention each year between 1995 and 2013.
Because the 290 participants were normal cognitively when the study began, the scientists were able to trace a number of biological and clinical features associated with Alzheimer's disease in the years before symptoms began. At the time of his last appointment, 81 people were diagnosed with mild cognitive impairment or dementia due to the disease.
Younes warns that changes to the brain vary in people and that the results of their research reflect the average level of variations of such in a small group of research topics, so that they cannot currently be used to compile. accurate conclusions, although they could serve to develop a test that determines an individual's relative risk of catching Alzheimer's disease. (Prensa Latina)