Wednesday , May 25 2022

Redefining Covid-19 is Possible And Should Inform Pandemic Priorities Moving Forward


A year after the discovery of the SARS-CoV-2 virus, the end of the pandemic seems just beyond the horizon as more and more people are still hoping for a highly effective vaccine soon. Returning to reality without Covid is an aspiration we all share, but there is reason to believe that we may never be free of Covid again because of the very real possibility of Covid-19 becoming an endemic disease; infected people can once again be re-infected.

Little is still known about the frequency of redefining Covid-19. There have been official cases across continents and there are undoubtedly many more that go unreported. A. Lancet the report confirmed that in mid-October, the virus had re-infected a man in Nevada. His symptoms were more severe during the second infection, but he has since recovered. Whether symptoms are worse on the first or second infection seems to vary from case to case.

That means that redefinition takes place despite the body’s immune response to antibody or T-cell production. Common knowledge suggests that when I’m sick, my body reacts immune to my specific disease to prevent illness. down the road. Although technically correct, an energetic immune response, including antiviral antibodies and T-cells, does not guarantee permanent protection against disease. While some antibodies last decades, such as measles, others may last six months or less. We do not know exactly how long our protective immune response to Covid-19 may last, but early indications seem to be weighing in for only a few months.

This may explain why confirmed redefinitions are so rare, as well as why many more redefinitions are probably taking place. If the first or second infection is asymmetrical, that infection can go undetected. Of the fifty-five million worldwide infections so far, it seems likely that Covid-19 has only re-infected more than five people.

Because of these uncertainties and the importance of redefinition, we call for a significant research effort to investigate this topic. This study would be constructed by first placing the virus of a large covid of Covid-19 patients on first presentation. Then we would follow them and test regularly with rapid antigen testing. These tests are the most efficient method of tracking the most infectious: asymptomatic and presymptomatic patients. The use of rapid tests means that the majority of this study could include asymptomatic and presymptomatic patients, whose sequences could be used for later research.

For each patient who tested negative and then later tested positive, we re-decide to determine one of two possibilities. Either the virus persisted and re-emerged, or it was a new infection. Only after two or three years of such studies can the true extent of redefinition be recognized.

Understanding redefinition is necessary to inform Covid-19’s management strategy going forward. Herd immunity strategists claim the potential to end the pandemic quickly and save the economy (at the expense of millions dead). They believe that a population exposed to the virus will trigger a widespread immune response and the development of antibodies and T-cells to a point where the virus no longer spreads. Although, if our immune responses fail over time and redefinition can occur, the herd immunity would fail along with them.

Our understanding of redefining SARS-CoV-2 will also have an impact on our vaccine strategy. Suppose a double dose of Covid vaccine only protects for months instead of years. In that case, we will need to reconsider the cost of manufacturing, dispensing, receiving a vaccine for multiple doses, frequency of immunization, and so forth. Studies of the New England Journal of Medicine a Science have noted that naturally produced antibodies can only last between two and five months. Vaccines may not be a silver bullet to stop the virus, but rather one of many tools to counter the pandemic.

All this research is preliminary, and the full extent of vaccine-based immunity will not be known until an approved vaccine has been in circulation for a long time. The vaccine maybe will be effective enough to eradicate the virus almost completely. We’ll have to wait and see, but we need to understand redefinition before we can understand what the best strategy to involve Covid is, whether it’s a vaccine or not. Be optimistic but be careful, because the pandemic is far from over.

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