Wednesday , May 25 2022

Researchers compare the risk of target organ damage in masked hypertension versus persistent hypertension


In a new publication by Cardiovascular Innovation and Applications, Yue Wu, Guoyue Zhang, Rong Hu and Jianlin Du of Chongqing Medical University’s Second Affiliated Hospital, Chongqing, China consider the risk of target organ damage in patients with masked hypertension versus persistent hypertension.

The authors compared the risk of target organ damage in masked hypertension (MH) and persistent hypertension (SH) through a systematic review and meta-analysis of PubMed, Embase, and the Cochrane Library of relevant case-control studies.

Articles on MH and SH were selected according to the inclusion criteria and were analyzed. The primary end point was target organ damage in the heart. The secondary end points were target organ damage in the kidneys and blood vessels.

Seventeen studies that met the screening criteria were included in the meta-analysis. Compared with the SH group, carotid intima-media thickness (IMT) and E / A ratio were significantly higher and the incidence of left ventricular remodeling and pulse wave velocity were significantly lower.

Other indicators in the heart, kidney, and blood vessels were not statistically different between the two groups. IMT ratio: P = 0.01, E / A: P = 0.01, prevalence of left ventricular remodeling: P = 0.02, heartbeat wave velocity: P = 0.01.

The study shows that MH may have almost the same amount of target organ damage as SH, so clinicians may need to consider target organ damage.


Journal reference:

Jianlin, D., et al. (2020) Risk of Target Organ Damage in Patients with Masking Hypertension versus Persistent Hypertension: A meta analysis. Cardiovascular Innovation and Applications. /10.15212 /CVIA.2019.1261.

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