LCR secretary Honda broke his right ankle in an accident in the field of February afternoon exercise for the Australian Grand Prix at Phillip Island last month.
He had an initial act to stabilize the injury, but a full surgery had to wait until the zoom was reduced.
Although it was immediately apparent that the injury was likely to end during its 2018 season, Crutchlow said he had hoped to start back for the season term in Valencia this weekend and subsequent tests.
"The injury I got could take a recovery time of up to 12 months and, although I think I would be back in time for a GP of Valencia, unfortunately, this is not the case," he said.
"I can not put pressure on my ankle for six weeks, but I'll continue to recover and get physiotherapy.
"This week, I will start trying to cycle again and look forward to preparing for Sepang [testing] in February 2019. "
Honda test driver, Stefan Bradl, will now substitute for Crutchlow in Valencia.
Crutchlow had to spend 12 days in hospital in Melbourne following his accident, with Lucio Cecchinello, the LCR team manager staying with him until traveling to the next Malaysia GP.
"I had excellent surgeons at Matthias Russ and Dr Evans who put an external driver on my couch to get started until the spell goes down and they can operate, which was six days later," added Crutchlow.
"The accident led to a pylon cut of Tibia, fibia and tall bones." The surgery was completed in three and a half hours and, together with reconstruction with artificial bone, two metal plates and eight screws were installed. "
Prior to his accident, Crutchlow had been fifth in the championship and team leader that was not the leading factories.
He is still seventh in the stalls, and the best driver of Johann Zarco of Tech3 Yamaha has just one point of front.
MotoGP has two post-season experiences this year – in Valencia following a GP this week and in Jerez a week later.
Sepang's 2019 tests in Crutchlow aim to start on February 1-3 next year.