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Hypothyroid overlap patients could increase the risk of stroke, study findings



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According to a new study, patients who take medication to treat hypothyroidism, can be treated with too much medication can lead to increased risk of atrial fibrillation, a stroke-related heart rhythm disorder.

The findings were presented by researchers from the Intermountain Medical Center Heart Foundation at Salt Lake City at the American Heart Society's Scientific Session conference in Chicago.

"We know that patients with hypothyroidism have a higher risk of atrial fibrillation, but we did not consider a greater risk of what is considered during the usual thyroid hormone. These findings show that we could We want to reconsider what we can do as usual. "Lead investigator Jeffrey L. Anderson said.

For the study, researchers examined the electronic medical records of 174,914 patients treated in the Intermountain Healthcare facilities that recorded their thyroxin levels (fT4) for free and were not on thyroid replacement medication. Then, researchers took what was considered during normal intervals of phT4, and divided into four quartiles, and then checking those patients' records for a current or future diagnosis of atrial fibrillation.

A 40 per cent increase in the current Atrial fibrillation was found for patients in the upper quartile of fD4 levels compared to patients in the lower, and a 16 per cent increase in Atrial fibrillation newly developed during 3 years of sequence.

These findings suggest that the best possible range of fT4 should be reconsidered and redefined, according to Dr. Anderson.

"Thyroid hormones are associated with weight loss and more energy, which can lead to people at the top of the normal range. Do we harm people by putting them at higher risk of atrial fibrillation, and therefore stroke ? "Said Dr Anderson.

The study also showed that fT4, along with a thyroid-stimulating hormone (TSH), which is proven more commonly in patients with irregular thyroid hormone levels but which did not help within the range normal when refining risk.

"The next step for researchers is to hold a random test to see if targeting a higher higher level of fT4 in patients with a replacement of thyroid hormone replacement therapy leads to a lower risk of atrial and stroke fibrillation and other issues. , related to heart, such as atherosclerosis, "said Dr Anderson.

Published: November 11, 2018 2:01 pm


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