In March, a study showed that around a third of French people slept during the week, less than six hours a night. Sleep time that could jeopardize their cardiovascular health. As a result of disruption to some physiological regulators, tell the researchers today.
People who are sleeping are slightly more likely to suffera the others. Several studies have already shown that. And today, researchers of the The US seems to have revealed the basic mechanism at the end .
these, contains about twenty , one of the main ways of regulating the . And that's why scientists are particularly interested. They hope that treatments that correct the changing signatures of these microRNAs could help fight diseases like .
Sleep at least seven hours a night
So researchers at the University of Colorado have measured in their patients the expression of nine microRNAs already associated with a, immune function or vascular health. As a result, people who do not have enough sleep levels of miR-125A, miR-126 and miR-146a are 40-60% lower than those who sleep & # 39 n normal.
"We don't know why seven to eightit seems to correspond to . However, it is credible that people need at least seven hours the evening to maintain important levels physiological, like these microRNAs » tChristopher DeSouza, physiology professor. Research is underway to determine whether recovery of healthy sleep patterns is sufficient to restore microRNA levels.
What to remember
- Poor sleep is associated with cardiovascular disorders.
- Reduced microRNA concentrations can explain why.
Sleep: good sleep protects the arteries
Good nights sleep promotes cardiovascular health. But for what reason? Researchers have noted in the mouse mechanism that would explain this phenomenon; it includes aproduced by the. t who would act on that and blood vessels.
Article fromPublished on 17/02/2019
In France, backone in three people suffer from it . However, different studies have found a link between sleep problems a like the , y , cancer, as well as cardiovascular disorders. But what can cellular and molecular mechanism explain this link between sleep and cardiovascular health?
In this study was published, the researchers Harvard Medical School from Boston focused on hardening , or . For this they worked on genetically modified mice to develop . Some mice could sleep as normal, while others were disturbed by sleep.
Over time, mice who were sleeping had more arteries in their arteries: their plaquesabout a third more. They also had in their blood twice as many cells known to be inflamed, some of them , compared to other mice. In addition, their hypocretin level – nerohormone produced by the – lower.
There are hypocretins, or orixins, in neuropeptides that get their name from contraction between the words "hypothalamus" and "secretins". yThe hypothalamus that produces the hypocretin has projections that can be directed to other parts of the t . According to the hypocretin injection induces vomiting in the rat. Hypocretin plays a role in the and wake up.
Research opening the way to new treatments
For the authors, hematopoiesis controls sleep, that is, productionand protects against atherosclerosis in mice. The mechanism is as follows: certain bone marrow cells, precursors , they have hypocretin receptors; in the presence of hypocretin, the mice have fewer circulatory monkeys and less atherosclerosis. In contrast, without hypocretin, mice have more bonnets and atherosclerosis.
The researchers also proved the effect of hypocretin supplementation in mice. As a result, hypocretin allows mice sleeping poorly to produce less inflammatory cells and develop smaller lesions compared to non-supported mice.
These findings suggest that a poor fall comes with a reduction in the level of hypocretin that promotes inflammation and atherosclerosis. But he will do further work to find out if this connection exists in humans too and if hypocretin can be used as a t.
In aFilip Swirski, one of the authors of the study, explains: "We have identified a mechanism for a The brain controls the production of inflammatory cells in the bone marrow to protect the blood vessels from harm. " But for this beneficial effect to happen, good sleep is essential: t "This mechanism is regulated by sleep and falls when you are often disturbed by sleep or have poor sleep quality. "
Take nap to prevent high blood pressure!
Article by Claire Peltier published on 14 December 2010
For National Hypertension Day, take time to look at your sleep. In fact, high blood pressure could be linked to rest too short or not very qualitative.
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Hypertendus, are you sleeping well? This is the question asked by the. Ton the occasion of National Anti-Hypertension Day.
It is also a titleIt is intended that everyone should realize that sleep helps to regulate the sleep . In fact, the heart and falls during rest periods. Studies have shown that there is a shortfall (less than 7 hours a day) or poor sleep quality ( , …) often associated with high blood pressure.
Restore your cardiovascular system
ShortIt also seems to have a beneficial effect on the cardiovascular system, but, unlike them naps, it would not be possible to sleep with the night.
To be interested in sleeping yourself to improve it, it could help to keep someone's heart. So don't hesitate: talk to your doctor.
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