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Antibiotic abuse, overuse of an increasing threat that needs to be addressed, says experts



Sheryl Ubelacker, The Canadian Press

Published Friday, November 16, 2018 8:10 AM EST

Updated Friday, November 16, 2018 9:38 EST

TORONTO – With the cold season and flu, some patients will not be sure to go to their doctors who are trying to prescribe for antibiotics, although the drugs are useless against viruses kind.

There is a misuse and misuse that has helped an increasing number of bacteria to resist most or all antibiotics – phenomena doctors call a crisis because there are no new drugs in the pharmaceutical pipeline displace.

And not just patients and doctors are blameless: decades of liberal use of antibiotics to promote the health of farm animals that lead to our boards and environmental contamination from the existing drugs have led to overlaps of & MRSA and VRE name that have developed resistant to their effects.

But fundamentally, the fact that antimicrobial resistance is a natural phenomenon, which is a process of bacterial development that has been taking place for thousands of years, says the director of the Institute of Infectious Disease Research at McMaster University.

"What's frustrating, of course, is that our overuse of antibiotics when they do not need them contributes to this option," he said from Hamilton. "If we create a situation where we use antibiotics when we should not, then we create increasing weight that increases the chance that the bacteria develop into resistant organisms.

"And that's the issue that we are currently finding that bacteria are increasingly in the clinic where we use many irresponsible antibiotics to all drugs we have available to no. "

The difficulty is that the pharmaceutical industry is no longer investing a time or money looking for new antibiotics, says Wright, explaining that science is not only "very hard," but it finds drugs from any Such is extremely expensive.

Drug manufacturers are not prepared to commit the average reduction of $ 1 billion to develop antibiotics that can improve infection within five to 10 days, when they can give their resources medicines for conditions such as high cholesterol or blood pressure, Usually taken for life.

Add that to the fact that a new antibiotics could have a limited shelf life because the bugs that it intends to handle can develop resistance and there is little incentive, Dr. Andrew Morris, director of the antimicrobial stewardship program in the Sinai System and University Health Network in Toronto.

Morris said that the lack of new antibiotics was also a matter of civil society, because people took these drugs for granted widely since the 1940's.

"So we can have a cancer drug that can stretch life some six months and that can cost between $ 5,000 and $ 100,000," he said, "And on the other hand, we can get an antibiotic that will save someone's life in full and we will get up in arms if that drug costs more than $ 1,000. "

An online national survey that quantifies information from Canadians on the issue found that 60 per cent of respondents believe a mistake believe that antibiotic resistance means that someone with an infection is resistant to the drugs. Released for the World Antibiotic Resistance Week, which ends on Sunday, the Leger survey found more than 1,500 of 18-year-old Canadians who found that 44 percent saw resistance as a greater concern for developing countries.

"Antimicrobial resistance is affecting everyone, everywhere, and that includes Canada, where there is an increasingly serious concern," said Morris. "The global health issue is truly the guarantee of joint action."

By 2050 it is anticipated that drug-resistant infections will result in approximately 2.4 million excessive deaths in developed countries alone, according to a recent projection by the Organization for Economic Cooperation and Development (OECD), which is 39 ; n represent nations such as Canada, Australia, USA and UK

Other experts have warned that the annual death toll due to antibiotic resistance will rise to 10 million worldwide – dwarfing cancer – and cost US $ 100 trillion the global economy.

"In literally, the worst thing that could happen is that we will end the way in the 1920s and 1930s again," before finding penicillin, when more people died from infection than any other individual case , says Wright.

"There are people who die today in Canadian hospitals five years ago they would not have died of their infection," said Wright.

"It's not necessarily thousands of people. People do not leak dead in the street. There is no zombie apocalypse," he said.

"But we have people in our hospitals that we have not been able to handle."

And not just those who already have infections that resistance could affect them, he says. "It will return to time when you can not make an organ transplant because you're compromised and immune for the rest of your life. You will not be able to rescue premature babies, treat leukemia.

"The things that we consider are quite regular today are going to be, or if they do not go, very dangerous."

Wright and Morris emphasize that cohesive action is now needed to stop the resistance of resistance, which means that the federal and provincial governments play a leading role in co-ordinating innovative programs to encourage antibiotic development, to find treatments alternative, and to misuse misuse and misuse.

"We're really at this perfect storm level and it's disappearing not every center – not all Canada is currently affected at the moment – but we do not; Getting the people of Canada everyday is affected by now and it will become increasingly aggravated, "Morris said.

Preventing a global war or some emerging catastrophic virus, I believe that the biggest healthcare threat that moves around the world is completely resistant to antimicrobial resistance . "


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