Monday , April 12 2021

A simple sugar supplement can slow down cancer growth & # 39;



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Hot cells use even more glucose than healthy cells

Researchers at the University of Glasgow have found evidence that a simple sugar supplement can slow down cancer growth.

The Beatson Foundation Cancer Research UK (CRUK) team also found that chemotherapy could be more effective against some tumors.

They did their mice experiments but they said one day could lead to human treatment.

The Glasgow study may refer to a way of "salt" cancerous cells.

All cells in our bodies feed on the sugar glucose. Tumor cells eat even more.

The team, led by Professor Kevin Ryan of the University of Glasgow, fed mice with other sugar tumors of the sea name.

Smoke occurs naturally in many fruit. I'll also do some cells in our bodies.

Its molecular structure is almost identical to glucose but the small difference seems to be a key key.

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The mice had different types of tumors. Someone was given someone three times a week through a feeding tube. Others were continually getting in their drinking water.

Writing in Nature magazine, Professor Ryan's team, said that the mice did not show any obvious side effects from the sea. Even more importantly, the sugar seemed to really reduce the growth of certain types of tumors.

The process was repeated, this time with the widely used cisplatin and doxorubicin chemotherapy drugs to see if the mose increased their effectiveness. In some cases, tumor growth seemed slow and there were actually some mice in the lifetime.

Fewer tumors

The reason? The tumors that are hungry for glucose are hidden. Mannose seems to get on the way.

The experiments suggest that the sea is not as much as a glucose block reaches the cancer cells but rather affects how those cells try to use glucose

A key sign that it works is the presence of an enzyme of the phosphomannose isomerase (PMI) name. Teens are associated with lower levels of PMI in cancer cells.

The Beatson Institute researchers tested this aspect of human cancer cells in the laboratory.

The ovarian, kidney, breast, prostate and bowel cancer cells were among the ones that were tested. The lower PMI levels were found with bowel cancer cells. Mice with the same cancer has also developed much less tumors.

However, there are significant caveats. This is not a cancer cure. It may not even be a treatment.

Moving from this discovery to something that can be given to patients take years.

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Experiments have only been carried out so far but one day could lead to human treatments

Professor Ryan says the results are promising but further research is needed to confirm the findings.

He said: "What we have to do is take to pre-clinical steps.

"Of course, anything that's going on as a person's treatment would have to be tested.

"We are taking forward clinical trials as quickly as we can."

A positive aspect of that is that the sea has already sold as a dietary supplement. Doctors can be prescribed as a short-term solution for urinary infections.

But the implications of long-term treatment are not known.

& # 39; Glimmer of hope & # 39;

Headteacher's nurse at CRUK, Martin Ledwick, warns cancer patients not to prescribe on the sea.

"This is a very early research," he said.

"There is a real risk of negative side effects that have not yet been tested.

"It is important to consult a doctor before significantly changing your diet or taking new supplements."

The Beatson Foundation research was jointly funded by CRUK and a charity based on St Andrews's Worldwide Cancer Research (WWCR) charity.

WWCR's chief executive, Dr Helen Rippon, says that he gives "hope of hope" that easily available sugar can become cheap and safe for cancer treatment in the future.

"At the moment it's too early to say that will benefit people as well as mice.

"But saving lives begins with discoveries like this."


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