Monday , November 30 2020

They solve red genetic mystery



The enigma of orange hair is much more complicated than a thought of it.

So far, it was considered that children need to inherit two copies of a gene called babies to be born MC1R, one by the mother and another from the father.

The MC1R birth is a regenerative gene, that is, it can not manifest itself in a prominent gene pair and only when the person receives copies of the mother and mother.

However, not everyone who inherits a MC1R orange hair gene, so scientists have doubted that other factors play an important role.

What were those factors that were a mystery … so far.

A study of the University of Edinburgh in the UK has just shown why the MC1R gene only explains part of the post.

Genetic differences

The study, developed by scientists at the University of Edinburgh, is More genetic research has to do on redheads so far.

Other Scottish researchers have tried in the past to explain the key to orange hair.

About 1 to 2% of the world's population is red, but in Scotland the percentage is close to 13%, which equates to 650,000 people, according to the ScotlandsDNA project.

Scientists at the University of Edinburgh examined the DNA of almost 350,000 people who participated in the British project of the name UK Biobank, which collects health and genome information of over 400,000 people in the United Kingdom.

When researchers took as much as the genome of redheads with people with brown or black hair, they found eight differences in hair color.

And they have also found that some gene control when MC1R is expressed or not.

Orange orange is not derived from a recruiting gene, but from complex interaction at least eight gene.

Blond brown

The researchers also saw almost differences 200 genyn which is related to people with blond or dark hair.

There is a color gradient that goes from black to dark brown, brown and blond light. And that gradient is caused by an increasing number of variations in those 200 gene.

Something that is surprising scientists is that many of these genetic differences are related to pigmentation, but with the texture of the hair. And other variations determine how the hair grows, that is, one that's just or circular.

"Our work analyzes most of the genetic fluctuations that contribute to hair color differences," he said. Albert Tenesa, one of the researchers of the University of Edinburgh Roslin Foundation.

Ian Jackson, a genetic specialist at the same center, said the work was an example of the "UK Biobank force, a unique genetic study of the United Kingdom that enabled us to make these findings."

The study was published in the journal Nature Communications.



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