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The Genetic Edition Congress condemns He Jiankui Science experiment



Nobel Laureate, David Baltimore, chairman of the organizing committee of the International Summit II on Human Genome Designation, condemns the work of scientist He Jiankui. In a video, Jiankui arguments with another genetician.

The Hong Kong Human Genetic Edition Congress, where the Chinese scientist, He Jiankui, has defended his experiment with viable human embryos, has changed his genes so that two twin-resistant AIDS twins are born , has closed with a statement of condemnation when considering the "scary" and "irresponsible" research. The Chinese government has ordered the paralysis of the experiments, something that the researcher has already decided to face the global conflicts that have been produced.

"Even if the modifications had been checked, the procedure was irresponsible and breaking all international standards," said the final decision of the congressional organizing committee, which ended this week in Hong Kong.

The decision calls for an independent evaluation of He Jiankui investigations, which has argued that he has changed using the Crisp Cas9 technology of the gene that uses the AIDS virus as a portal to the system Immunity in two embryos having vitro fertilization and from both named babies, According to the scientist, they are fine. I have also admitted a second nutrition with genes that have changed.

These researchers have not been contrasted by any independent scientist or any of the organizations with whom the geneticist is involved or any ethical committee has acknowledged that they have been informed of the experiments, as established by the standards.

Last Monday, the surprise announcement of the birth of two genetically modified babies for the first time caused a great stimulus in the international scientific community. Jiankui appeared in a video that was placed on the network where he explained an experiment that had probably made it confidential and without the appropriate ethical and clinical requirements.

On Wednesday, what was his first public appearance since he revealed that he had successfully changed the DNA of two newborn twins – Nana and Lulu – in their embryonic phase to resist AIDS virus infection, he was proud of & # 39; to a desired achievement and he opposed criticism and confessed that this is the only way to improve any disease. But his speech did not convince part of the audience.

He should have taken part on Thursday in another panel of specialists, but finally canceled his "self-determination" appearance, according to the certainty of the Nobel Nobel Prize of David Baltimore, a genetics copper organizer.

Results

Many experts have warned of the consequences that this adaptation can have on people in future generations. "By doing this, we are changing the human gene fund, we may not see this effect until several generations later," said Dennis Lo Yuk-ming, chairman of the Department of Chemical Pathology at the University of China in Hong Kong. . He said that there is still no academic consensus to maintain this type of test among people.

However, the path to achieve that agreement could begin to be compiled by recent events. The congressional committee of the congress noted itself, despite these obvious difficulties and risks, "the progress in the past three years and the discussions at the current summit suggests its It's time to define a thorough and responsible way for such trials ".

From the other side of the Pacific Ocean, the president of the National Academy of Sciences and the National Academy of Medicine of the United States, Marcia McNutt and Victor Dzau also expressed their concern to note that "what happened in Hong Kong this week clearly shows we need to develop more specific standards and principles that can be agreed by the international scientific community. "

But finding consensus among scientists from different parts of the world is not an easy task. As the biology specialist, Sarah Chan, said today, "we can not consider the international scientific community as an individual and unified body, it is a summary where there is a lot of diversity". For that reason, "we have to be sensitive to different situations in different contexts" without forgetting that this type of evidence – has done without transparency – "goes beyond to what's acceptable ".

While waiting for these intentions to bring fruit, he has respected his experiments. The reason: the scandal produced after the announcement and flood of criticism after the institutions and hospitals involved in the process denied their participation and began an investigation to try to explain the actions taken by the Chinese scientist.


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