Wednesday , September 28 2022

the bowel also produces its own blood cells


Not only the spinal cord: the bowel also produces its own blood cells


MADRID, December 3 (WASG EUROPA) –

The bowel has a reservoir of cells that form up to 10 percent of cyclical blood cells, according to research by scientists at the University of Columbia (United States).

So far, blood cells were believed to be created only in the bone marrow of a special population of hematopoietic cell cells. However, this reservoir, which was discovered by a team led by a Director of Translation Immunology Center in Columbia, Megan Sykes, apparently discovered that the blood of their patients who had received intestinal transplants included donor cells. .

The researchers traced the donor's blood cells to the source, the hematopoietic cell cells in the gift hut. The researchers indicate that the blood cells that give more donors to patients in circulation, the least likely to have their transplants rejected. "Patients with a high level of donor cells may not need as much immunization as they are currently being admitted, and reducing immunization could improve the results," says Sykes.

Expanding organs transplanted with additional hematopoietic cell cells by the donor can also increase the interference between the donor and the receptor and increase the tolerance of the transplant. "This could really improve the lives of transplantated patients, and ultimately aim to get immunological tolerance, which would allow us to eliminate immunization in completely and for the patient to handle the craft, which is the Holy Spirit, really a researcher

According to the scientists, the analysis of circulating white blood cells in patients after intestine transplantation suggests that the cells that result from the given bowel mature and have been taught in the receptor to be tolerant to the tissue of the recipient themselves. Similarly, white blood cells produced by the recipient after transplant can be taught to tolerate given tissue.

"We clearly show that there are interventions between the two groups of blood cells that protect the transplant of the patient's immune system and protect the patient from transplanting," says Sykes. Because patients with more donor blood cells have lower organic refusal rates, the results refer to new organ transplant management strategies.

Now, researchers are planning a study that will seek to increase the number of hematopoietic cell cells during the bowel transplant, which will lead to higher blood circulation levels of the donor, immune tolerance and reduced need for antisocial drugs.

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