Sunday , April 11 2021

Scientists from Chile discover antibodies that protect the Andes hantavirus



This finding could also be applied to people, said María Inés Barría, a microbiologist and co-ordinator of this research, which began in 2014 and the first collections today were published in the Science Translation Science magazine.

Haunt infection is an infection that transmits cruelty to people and subtitles of the Andes, which affects the Chilean and Argentine Patagonia area, is the only one that has shown that it can be shared between people too.

Andes hantavirus infection leads to a highly dangerous condition known as cardiopulmonary syntactic syndrome (SCPH), which can cause fever, headaches, low blood pressure and heart failure and lungs, and which is a cause of concern big because it is high mortality rates.

Antibodies of those who survive

The results of the investigation showed that the antibodies of human survivors protected the animals from suffering the SCPH even when they were administered after the infection of Andes hantavirus.

This suggests that they could be used as a disease exposure preventive treatment that currently has no improvement options, according to the research.

"So far there is no specific treatment for this infection, the only thing the doctor can do is supportive treatment in the ICU," said Barria.

In 2017, 90 people had been infected with the Andes hantavirus, 24 of them died of the SCPH.

Groups that are vulnerable

The most vulnerable groups to this infection are people who live in rural areas or who work in agricultural or forestry areas and have many cases in young men .

The investigation method was the isolation of antibodies from 27 patients who survived the Andes hantavirus or which showed tougher symptomatology.

The next step was to spray hamsters with a deadly dose of the virus and then put them into human antibodies, and in each of them the SCPH was stopped and survived.

"The hamsters were used because the most similar model is the symptomology and pathology of people," Barría explained.

At the moment, the University of Concepción also develops a dose that is suitable for people and is therefore able to experience in the experimental trial of the effects of the effects of the virus that have been as successful as puppies.

Also, once it has been proven that the method prevents the development of SCPH after it has been infected by Andes hantavirus, scientists want to study in mice if it is also working to prevent this virus infection.

"Our idea is also to prove it as proxylactic with animals, to administer dose before the infection, so we would increase the operating spectrum of these antibodies," added Barría, who hopes that a substance can be developed; n prevent infection with this perception.

The expert noted that he could serve as a "short-term vaccine" due to the antibody feature "people would be protected for a short time".

"Even if the defense lasts for three weeks or up to two months, it would also be useful for the risk groups: forestry workers, agricultural workers, tourists who went to Patagonia or even to face a big cause of hanta, "he added.

The researcher also noted that this finding could be a cure for other hana presence in Europe and Asia.

"The technology is not the problem, the appetite or the ideas, but we need the funding to know how far this investigation can go," Barria came to an end .

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