Friday , September 30 2022

Body fat levels associated with breast cancer risk in post-class women



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"We find excessive body fat in those suffering from men's men with a normal physical mass index associated with doubling the estrogen-dependent breast cancer," said Dr Andrew Dannenberg, one of the study authors and director of cancer prevention at the Sandra and Edward Meyer Cancer Center at Weill Cornell Medicine.
The American Cancer Society says that estrogen-dependent cancers, known as ER-positive breast cancer in the study, occur when the receptor proteins in or on cells attach and depend on the hormone's estrogen to grow
The researchers studied 3,460 American women aged 50 to 79 who had gone through the menopause. The women were part of the Women's Health Initiative and their body composition was measured at the beginning of that program, Dannenberg said. Of those women, 146 breast cancer developed ER-positive, and researchers were looking for an additional body fat relationship and the development of this cancer.

An increase of 5 kilograms (11 pounds) in whole body fat mass was found to be associated with an increasing risk of 35% of this type of breast cancer. An increase of 5 kilograms in the fat mass of the trunk road associated with an increase of 56% was at risk.

Horse fat "is defined by the fat contained in the torso other than the head and the members," according to the study.

The study also found that invasive breast cancer, which has spread into tissue and breastfeeding, increases an increase of 28% in whole body fat mass associated with a 28% increase. The same increase in the trunk was associated with an increase of 46% in the risk of invasive breast cancer.

"The main catch is that there is too much body fat, even when you have a normal physical mass index, associated with an increasing risk of breast cancer," said Dannenberg.

Individual BMI is calculated through a formula that includes their height and weight; BMI "normal" is considered between 18.5 and 24.9, according to the study.

The researchers also looked at blood data obtained at the start of the Women's Health Initiative for other factors known to be involved in the development of breast cancer, such as insulin molecules.

The results "highlight the importance of research that distinguishes body size, body composition, and metabolic profiles to breast cancer risk," Drs. Isabel Pimentel, Ana Elisa Lohmann and Pamela J. Goodwin wrote in an editorial published alongside the study.

The editorial authors also point out that other researchers have looked at the subject with different results and "these comments suggest that components of metabolic health, rather than the presence of full metabolic syndrome, can contribute to breast cancer risk. "

How much a decade of obesity is your risk of cancer
One of the special strengths of the research to Hoda Anton-Culver, a distinguished professor at the Department of Medicine at the University of California, Irvine was a breakdown of the location on the body of fat levels.

"I think it's a good step forward that takes us from looking at the BMI as an obesity indicator to look at the specific site of the fat concentration in the body," said Anton-Culver, who was not involved from the research.

Scientists have known that there is a link between obesity and cancer, but Anton-Culver says that the new study is moving the research beyond that general society.

"They say correctly in the summary that obesity is related to breast cancer, but more specifically, obesity around the abdomen is more specific for that society," he said.

Although Anton-Culver believes that the research was strong, he noted that he was only looking at specific cancer.

"I do not know if we are looking at the same issues as other cancers as the result, what will happen, is it specific to breast cancer?" he says. "We need to ask that next question, because obesity is a risk factor for other cancers."

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