Wednesday , September 28 2022

A little child needs extremely rare blood to beat cancer. The world helps him to find it



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He explained the biopsies and blood tests, which explained Zainab Mughal's blood trial, said his parents were going to tackle the sudden complexity of fighting their daughter's cancer. For the two years of age to survive, it would take something that they had no control over: The kindness of strangers.

Zainab, who lives in Florida in the United States, has been diagnosed with neuroblastoma, abnormal cancer that usually occurs in children. Doctors said the tumor had been growing inside the Zainab abdomen for almost half of its life. The fight would require two bone marrow transplants and a series of transfers to replenish its blood supply as chemotherapy squeezes the tumor to no, doctors say.

"The results came in and the results were very bad," said her dad, Raheel Mughal, in a video. "We all cried. This was the worst thing we were expecting."

There was another great complication: Mughal and a woman tested to see if they were compatible blood donors. They were not. A family march and friends went to hospital to be taken by needles. No luck

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"And that's when it became more notice," said Mughal.

Toddler Zainab needs blood transfusions as chemotherapy takes tuberculosis.

SCREENSHOT / POST WASHINGTON

Toddler Zainab needs blood transfusions as chemotherapy takes tuberculosis.

Now, the two years old are at the heart of a global search to find extremely rare donors who can help him, a battle depending on the statistics and the likelihood that his parents have become too familiar with her.

The people who are most likely to have a suitable blood from Pakistani, Indian or Iranian decline, according to OneBlood, are the non-profit blood center that leads the search. But even in those populations, less than 4 percent of people have blood that Zainab's body will not reject.

Most people do not have to go to the world that is hidden and often from rare blood transfusions.

There are about 360 different antigens on the face of red blood cells, but most people's organizations will not react negatively to those markers, says OneBlood's reference lab, Frieda Bright. For most people, getting the right kind of blood is all important.

But a small percentage of people – including Zainab – produce antibodies in the presence or absence of some antigens, encouraging the body to refuse the blood. But those people are still in accidents or coming down with diseases like everyone else, so there is a network of blood centers that specialize in unusual blood, keeping a database of rare combinations of antibodies antibodies and turn it to patients who need it.

That's a big part of Bright work. It is part of a team that works around the clock, 365 days a year, to identify and catalog scarce blood units and, where possible, to complete applications. Still, the Zainab case is so scarce that Bright – who has worked in the industry for 20 years – has had to go to a textbook to learn more about it.

Now OneWlood is working with the American Curious Donor Program, an organization that connects donors with needy patients all over the world. For Zainab, three matching donors have been found – one lives in London, and the other two are in the United States.

That's a promising sign, but it's not enough. The rules limit how often donors can give blood. Zainab doctors would have to make up to 10 donors to ensure that when Zainab needs a blood transfusion, he can get it.

Here's the missing piece of a treatment plan that doctors already say shrinking Zainab's tumor.

More than 1000 people of Iranian, Indian or Pakistani disagreement have given blood in an attempt to see if they are compatible with Zainab.

But her parents and a team of experts realize that this has not happened until Zainab goes out of hospital, cancels are free. So they have launched an awareness campaign using the best tools they have: Zainab's story, and endless numbers of unusual baby pictures – occasionally – babies. One shows the little boy wearing a birthday party and a polka-dot pink dress, another shows her for a photo with dress and flowers cream cream and ribbons in her hair. A third, post-diagnosis, shows huge brown eyes under the top of Mael.

She is still too young to get full grasp of the gravity of what she needs or the overwhelming limitations that are being tackled against her. But her father hopes for one day explaining her how a group of people who did not know helped her save her life.

"It's a poor application, and I'm asking for it by my heart," said Mughal in a video produced by OneBlood. "My daughter's life depends really on the blood …

"What you do to save human life, to save my daughter's life, it's amazing. Once my daughter grows, I'll be reminded that the an effort to make you save your life. "

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