Tuesday , May 24 2022

COVID-19: Why diabetes and hypertension increase brain complications


It is thought that the virus that causes COVID-19 first attacks cells in the respiratory system, most often leading to lung inflammation that puts patients at risk of pneumonia and respiratory distress. But the effect of the virus has now been recorded in other organs and tissues. has also been felt in other body systems. The study’s lead author, Dr. Colbey W. Freeman, of the Department of Radiology at Penn in Philadelphia recalls that “although brain complications are rare, they are often a progressive and devastating result of COVID -19”.

A COVID patient with a brain injury has pre-existing hypertension or diabetes

Dr.’s team followed. Freeman and Perelman School of Medicine COVID-19 patients assessed by CT and / or brain MRI during the period January to April 2020. 81 participants had a brain scan due to and altered mental state and focal neurological deficits such as speech and sight problems . Of those 81 patients who had brain scans, 18, or just over a fifth, presented results that were considered “urgent or critical,” including cerebral hemorrhages and stroke.

  • At least half of the patients had a history of hypertension and / or type 2 diabetes;
  • 3 of the patients died of critical events during admission.

So are hypertension and type 2 diabetes Often Associated with COVID-19-Related Neurological Disorders: This is the conclusion of the study that reveals a higher rate of overweight and / or diabetic participants who developed these complications. However, how to explain these connections, what are the mechanisms involved? The exact mechanisms are poorly understood and may involve several factors. The most widely shared hypothesis is that infection-related inflammation is the main driver for these (and other) neurological effects.

“When your body is in an inflammatory state, it produces all these cytokines to help stimulate the immune system and encourage it to perform its function. However, if there is a “cytokine storm” the immune response damages “.

The team continues to monitor the incidence of neurological complications in its COVID-19 patients and plans to conduct a larger prospective study to assess delayed, long-term, and chronic neurological manifestations.

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