Tuesday , January 19 2021

Genetic mutation leads to very rapid wound healing in patients in Scotland



How to protect a mutation of pain, wounds and fears

Scottish retirees appear to have much in common with the heroes of current Marvel films. The old woman hardly feels any pain and has a very strong ability to cure injuries. Researchers have now found that the woman's remarkable ability is due to mutation.

A recent study by the University College London and the University of Oxford, which was respected internationally, found that the 71-year-old woman from Scotland has virtually no mutation pain and can cure injuries very quickly, and often t without scarring. The results of the study were published in the English magazine "British Journal of Anesthesia".

Scars often leave scars on our body. An old woman suffers from mutation, so she feels a bit of pain and heals wounds without scarring. This could in the future lead to a new way of treating pain and wounds. (Image: gamjai / fotolia.com)

A woman noticed mainly the smell

The victim reported a number of burns and painless cuts. She often smeared meat to burn on burns before she even noticed the injury. According to the researchers, painlessness and severe healing are the result of a previously unrecorded genetic mutation. The case could open the door to a range of new treatments that help people to improve better after surgery and overcome chronic pain and anxiety disorders.

Researchers became aware of the mutation through hip replacement

Jo Cameron first attracted doctors' attention when she was treated for a hip problem at the age of 65. The hip was later classified as arthritic, and had to be replaced. The patient did not respond as expected to the debilitating procedure and after a second operation without pain, the doctors decided that the case should be investigated in more detail.

Wounds are usually cured without scarring

In addition to his detailed medical history, the victim reported a number of burns and painless cuts. The wounds or the subsequent burns improved extremely quickly and only a very small or no crude at all. The old woman didn't realize that she was so different to other people until she needed a hip. Until a few years ago, the woman had no idea that it was unusual to experience so little pain. The affected person was of the opinion that this was entirely normal.

FAAH-Out closes an important gene in the patient

In their study, researchers from University College London and Oxford University identified two notable mutations in the patient. One mutation was a gene of the name FAAH (fatty acid acid hydrolase). The FAAH gene plays a role in the body's endocannabinoid system, the parts of the central nervous system that play an important role in pain, memory and mood, and the compounds in Cannabis acts on them. They also found a second gene that was previously considered DNA without any useful purpose. It now appears that this gene, from the name FAAH-Out, manages the Faah gene and closes it down in Mrs. Jones. Cameron.

Patients were not afraid and never panicked

As well as wound healing and pain resistance, the woman had exceptional results in tests of anxiety and depression. She explained that she never panicked in dangerous situations, such as a car accident.

Insights could protect people from pain in the future

The effects of these findings are immense, explaining the authors of the study. Half of patients recovering from surgery have moderate to severe pain despite modern painkillers. The FAAH-out as it's called could be key to releasing the potential reduction of the FAAH gene pain if other treatments have already failed. The results suggest a new analgesic discovery that can provide pain relief after surgery and can also speed up wound healing. It is hoped that the new findings will help 330 million patients to have global surgery each year, according to the research team. The old lady was delighted that her genetic mutation could help other people suffering. (As)


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