Wednesday, December 12, 2018 13:37
Y Society of Argentina Bioleggens (SAB) was given the Jorge Ponce Hornos tucumana Award Florence González Lizárraga, which competed against 350 work of the area that was introduced from different parts of the country. The second mention was about another Tucuman, Luciana Medina.
The study presented by González Lizárraga, "COL-3 prevents the Alpha-synuclein pathological consolidation and remodels the conditioning of amyloid fibers: a possible compound for reusing as a neutro-preventive", at the Institute of Medical Medicine and Complex Cells (IMMCA) of triple dependency between the Tucuman University, CONICET and the Tucumán Ministry of Health, under Rosana Chehín.
According to the Science, Art and Innovation Technology Secretariat, the Advanced Microscopy Center (CMA) of Buenos Aires University also co-directed by Lía Pietrasanta.
González Lizarraga noted that COL-3 was a substance that was derived from tetracyclines, which was chemically modified so that its antibiotic activity had decreased. The advantage is that, as it is not antibiotic, it can be used for long treatments such as neurosurgery, avoiding the production of bacterial resistance.
The young researcher said that COL-3 would be better than doxycycline in terms of its neutro-preventative effect. This antibiotics has been studied by Tucumán researchers in recent years for its neuro-preventative effects. "We found that it has anti-inflammatory, antisocial properties that lead to the formation of non-synodin-toxin-free species to doxycycline, is that it has the ability to unlock the fibers that are; are added and that are toxic in Parkinson's disease- "he said.
On the other hand, the SAB awarded the second mention of Lucica Medina's Ponce Hornos Prize and Tucumana. He wanted her Study on the interaction of doxycycline in the Tau protein, forming less toxic species in Alzheimer's disease. The total amount of this protein is considered to be the main cause of neuronal death in this disease.
Three other Tucumán researchers took part in the conference: Benjamín Socias, Natalia Ríos Colombo and Fernando Dupuy. Participation was also recorded to integrate the board of directors of the SAB, through César Ávila who was an elected member.
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