Friday , August 19 2022

They created small kidneys to deepen renal research



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The scientific journal Nature Materials brings good news in renal research. A group of researchers from the Catalonia Bio-Feeding Institute (Spain) The creation of minirriñones in the laboratory of human multi-cell cell cells.

Multipotency cells have been triggered (iPS) are removed, for example, of skin or blood of people and four gene are added to their re-mapping. Therefore, they will look and act as embryonic cells, which will allow them to transform into any type of cell. In this case, in a 20-day period they form a kidney to an embryo size of 6 months.

Although something similar has already happened in 2013, the director of the Núria Montserrat inquiry into the news agency EFE this represents a qualitative bias: The organs have been completely formed by human cells, have a larger blood supply and have been developed in less time. "We succeeded in growing this organoid in biomaterial – hydrogel – which emulates the hardness of the embryonic environment. Thanks to a chicken embryo membrane, we also achieve vascularization, blood flow and even growth," explained the expert.

What will this serve? Its purpose is improve kidney research. Therefore, they can observe how the organ evolves if it is the subject of a variety of diseases or the way the drug is affected. Another long-term objective is the production of transplantable tissues, although they explain "we are still far from being able to transplant artificially created kidneys".

"This organ is very complicated, involving many basic diseases and another secondary affects it. So, we can analyze how they form the blood vessels, how they water, how they act and how the nephrons grow", Montserrat has finished.

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