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In a small study involving 35 patients, Israeli scientists claim to have successfully reversed the aging process in human cells for the first time by extending the length of telomeres, the structures that ‘cover’ the ends of chromosomes. The results of the research were published in the biomedical journal Aging.
As we grow older our telomeres are shorteningSince each time a cell divides, part of the telomere is lost, leaving each new chromosome slightly shorter than its predecessor, so its length is considered a marker of biological age. In addition, that shortening increases the risk of future mutations, which can often lead to age-related diseases, such as some types of cancer.
The study participants were subjected hyperbaric oxygen therapy (based on pure oxygen absorption in a pressurized chamber) for five 90-minute sessions a week for three months, and as a result, up to 20% was extended to some of the telomeres in its cells. That is, the telomeres in the white blood cells taken by those 35 people, all aged 64 and over, recovered about one-fifth of their lost length.
Although the scale of the research is too small to reach definitive conclusions, the simple fact that hyperbaric oxygen therapy may have an effect on telomere length opens the way for larger studies.
Shai Efrati, a professor at Tel Aviv University’s School of Sacred Medicine and the School of Neuroscience, explained to ScienceAlert that “longer telomeres are associated with better cell performance,” which is why studies are possible. or regaining their length has so much potential.
In a press release from the Sagol Center for Hyperbric Medicine and Research, Efrati noted that understanding telomere shortening “is under consideration Aging biology ‘Holy Grail’, although it is clear that the process of human aging extends well beyond the length of these elements.
Therefore, in their research, the scientists determined that the genetic changes produced by hyperbaric oxygen therapy not only prolong the telomeres, but also had a potential positive impact on the health of the tissues themselves. However, there are many additional factors to consider.
To reverse the aging process completely, we would need to restore some pieces of genetic code lost during cell division, something that occurs in certain tissues lining our intestines by an enzyme called telomerase. However, telomerase reactivation is a technique used by specific cancers to replicate, so scientists must also be careful when exploring that particular path.
“So far, interventions such as lifestyle modifications and intensive exercise have been shown to have some inhibitory effect on the expected shortening of telomere length. However, what is remarkable to observe in our study is that only three months of hyperbaric oxygen therapy, we were able to achieve such significant elongation of telomeres, at a much greater rate than any of the interventions or lifestyle modifications currently available. , we have opened the door to new research on the prolonged cellular effect of hyperbaric oxygen therapy to reverse the aging process, ”said study co-author Amir Hadanny, director of medical research at the Sacred Center for Hyperbric Medicine and Research.
Aging, ScienceAlert, The Truth, Youtube.
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