Wednesday , April 14 2021

ISS microbes should be monitored in order to avoid a threat to the health of astronomers



A smooth and smooth colonial growth of Enterobacter bacteria on Tryptic Agar Agar Broth. Credit: CDC

Bacteria Bees Enterobacter, which is similar to infectious organisms that take advantage of the recent news in some hospitals, identified on the International Space Station (ISS). The stresses found in the space were not pathogenic to people, but researchers believe that they should be studied for potential health implications for future trips, according to a study published in the open access magazine BMC Microbiology.


Researchers at the Jet Propulsion Laboratory, California Institute of Technology, USA investigated five types of Enterobacter which was isolated from space space and platform on the ISS in March 2015 as part of a wider effort to characterize bacterial communities living on surfaces inside & # 39 ; the space station. To identify species Enterobacter collected on the ISS and to show in detail the genetic make-up of the individual strains, researchers compared ISS types to all genomes that are publicly available from 1,291 Enterobacter Stresses collected on Earth.

Dr Kasthuri Venkateswaran, Senior Research Scientist in the Jet Propulsion Laboratory Biotechnology and the Planetary Watch Group and the author of the corresponding study, said: "To show which species of bacteria were present on the ISS, we used a variety of methods to characterize their genomes. Details We have revealed genomes and five ISSs Enterobacter The stresses were genetically similar to three types of news found on Earth. These three strains belong to one species of the bacteria, the name Enterobacter bugandensis, caused to cause disease in neon and compromise patients, who were admitted to three different hospitals (in eastern Africa, Washington to Colorado). "

Comparison of the genoms of the five ISS species to the three Earth clinical species allowed the authors to have a better understanding of whether the ISS types showed antimicrobial resistance characteristics, if they had similar gene profiles to & # 39; Those found in known resistant multi-drug bacteria, and to identify genes that are related to their ability to cause disease (pathogenic potential).

Dr Nitin Singh, the first author of the announcement, said: "Given the anti-drug resistance results for these ISSs E. bugandensis genomes and the increasing chances of pathogenicity that we have identified, these species can be important health considerations for future trips. However, it is important to understand that the strains found on the ISS are not burdensome, which mean that they are not an active threat to human health, but there is something to monitor. "

The authors found that the ISS islands have similar antimicrobial resistance patterns to the three clinical species found on Earth and include 112 genes associated with virulence, disease and protection . Although the ISS E. bugandensis stresses were not pathogenic to people, the authors are predicted through computerized analyzes, a 79% probability that they could cause disease. However, analyzes in living organisms should be carried out to confirm this.

Dr. Venkateswaran: "Whether a convenient pathogen likes it or not E. bugandensis causes disease and the degree of threat, depending on a variety of factors, including environmental factors. Further in vivo studies are needed to discover the effect that conditions on the ISS, such as microgravity, other space, and factors associated with a spacecraft, on pathogenicity and virulence. "


Further investigation:
Prost species used in a food industry cause people's disease

More information:
Nitin K. Singh et al, Enterobacter bugandensis Species isolated anti-drug resistant of the International Space Station and relative genomic analyzes with human pathogenic stresses, BMC Microbiology (2018). DOI: 10.1186 / s12866-018-1325-2

Magazine reference:
BMC Microbiology

Provided by:
BioMed Central


Source link