Thursday , July 7 2022

how is interpersonal intervention


Hantavirus's interpersonal transfer has been subject to study for a few years.

For the first time, the person-to-person assault was described in an emergency that affected 16 people in 1996 at El Bolsón. And now, it is assumed that the case in Epuyén has been spread in a party.

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In 2006, a paper was published in the specialist Infectious Disease magazine, which was conducted by researchers of the INEI (Malbrán Foundation), Buenos Aires Hospital, Buenos Aires, and the City of Buenos Aires Epidemiology Offices and Neuquén, directed by Dr. Paula Padula, where it was confirmed that the transfer between people occurred with at least two of the six known layers of the Andes (as called the aviation, which, in South America, is the main cause of hantavirus lung syndrome).

The inter-human infection of the Andes virus is similar It is more likely to occur during a long and close contact with an infected person and may be transmitted through small infective particles in the saliva.

Experts recommend special care for people who have been in contact with infected people in enclosed areas, in houses, in vehicles or in some work environments.

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Once an assault occurs, the incubation period of the disease varies between 12 and 27 days.

Malbrán's virologists guess that the transfer of the virus from one person to another occurs, during the initial stage of the disease – a prodomic period – or soon after that. "In this period," explained Dr. Padula, "that the first symptoms show themselves, which can not be resisted from other fake-flu cases in their initial stages.

It is characterized by the presence of exposure such as fever, headaches, muscle pain, weakness, rot, inflammation, diarrhea and diarrhea, among others.

The most likely period of infection is the end of the prodromal period and the start of the cardiopulmonary phase, which is when respiratory complications begin to highlight, he added.

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Padula noted that the number of registered cases in South America was increasing, with a current mortality and syndrome rate that ranges between 25 and 40%.

However, it is clear that we can not talk about an epidemic. "Of every 100 cases, it happened about one only because of an inter-human intervention," he said.

"The probabilities are very low. In the events studied, the transfer chain was not higher than the three loops"He said.

In order to prevent an attack, it is recommended that close ties with sick patients be avoided and for medical personnel to follow the general norms of biosecurity, including the use of chinstrap, camisole, gloves and goggles.

How was the investigation?

A step by step investigation is needed on the virus human transit route.

Once a person is known to Hanta's symptoms, and provided there is no evidence of exposure to beasts, questioned whether he had a prior connection with a confirmed case, contact dates, sickness dates were considered, and viral genetic identity is also analyzed.

This analysis includes comparing viral DNA sequences obtained from each patient to know if they are related to the same viral stress.

On the other hand, these samples are compared to sequences stored in a database to confirm which area the virus came from.

In certain circumstances, such as trips to endemic areas, or from one area to another, The possibility of inter-human transmission is easier to check.

If the contact dates between the two people are associated with the start dates of the disease and, if the virus genetic characteristics that correspond to each case match, then the transfer by human transfer will be confirmed .

So far, no effective vaccines or antiviral drugs have been obtained for prophylaxis or the treatment of Hantavirus infections.

For now, preventative measures It is the ones that allow to limit the increase of this disease.

Source: CyTA / Leloir Institute

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