Thursday , May 26 2022

Sperm counts 50 percent lower in the sons of smoky fathers


Studies have often linked to smoking mothers during pregnancy, with lower sperm rates among men. Now, a research team at Lund University in Sweden has discovered that, independently of the mother's nicotine exposure, that men whose patients smoke during pregnancy have half as much sperm as those with fathers they did not smoke.

The study was carried out on 104 Swedish men aged 17 to 20. Once the researchers had adapted for their mother's exposure to nicotine, socio-economic factors, and smoking and their own children, smoking-makers with 41% centered sperm and 51 percent less sperm than men with non-smokers. The research team at Lund University is the first to identify this perception.

"I was surprised that, despite the mother's level of exposure to nicotine, the sperm count of the men whose dads are so much lower," said Jonatan Axelsson, a specialist doctor in occupational and environmental medicine.

The binarker cotton is a blood-metabolism of nicotine. By measuring cotinine level, researchers can see if the parents themselves smoke or have been exposed to passive smoking. Many previous studies have shown that it is harmful to the fetus if the mother smokes but, in this study, there is a link between the practice of smoking and father and sperm count the son is even clearer.

Jonatan Axelsson can not explain why this is the case and believe that more research is needed to understand the basic mechanisms. On the other hand, it is clear, similar studies have also shown links between smoking fathers and various health outcomes in children, such as malformations.

"Unlike the mother's pum, father's gamets are constantly sharing throughout life and mutations often occur exactly in the cell section. We know that tobacco smoke contains a lot of Substances that cause mutations, so one can imagine, at the time of conception, the gamets have had mutations and thus passes genes that lead to the reduction of sperm quality in men's birth. "

Most of the recent conversations (known as novo mutations) come through the father and there are also links between the father's age and a number of complicated diseases. In addition, researchers have noticed that smoking is associated with DNA damage in sperm and smokers have more breaks in the DNA strand. It was reported that the children of children who smoke up to four times so many mutations in a specific repetitive part of the DNA as children of non-smokers.

"We know there is a connection between sperm counting and pregnancy opportunities, so that could affect the possibility that these men will get children in the future. The father's smoking is also associated with shorter reproductive life In women, so the idea that everything depends if the mother smokes or does not seem convincing. Future research may move us closer to a causal loop ", in finishing Jonatan Axelsson.


Disclaimer: AAAS and EurekAlert! they are not responsible for the accuracy of news releases posted to EurekAlert! by contributing organizations or for using any information through the EurekAlert system.

Source link